Saturday, September 02, 2006

[health] canadian breakthrough on birth defects

New research shows that ensuring an adequate intake of vitamins and minerals by taking a single, cheap pill on a daily basis sharply cuts the likelihood of a wide range of severe birth defects, including neural-tube defects such as spina bifida, brain-damaging hydrocephalus, heart malformations, truncated or missing limbs, urinary-tract abnormalities and cleft palate.

"The data are really very striking. It seems almost too good to be true that a prenatal multivitamin can have such an impact. But it is true," Gideon Koren, director of the Motherisk Program at the Toronto Hospital for Sick Children, said in an interview.

Based on the study, he said all women of childbearing age should be taking a prenatal vitamin daily. Dr. Koren said the recommendation should apply to all women but he stressed that they should take a specific prenatal multivitamin. These differ from standard multivitamins in three important respects: More folic acid, more iron and less vitamin A -- high levels of which can harm the fetus.

This results in a:

# 48 per cent reduction in neural-tube defects;

# 39 per cent drop in cardiovascular defects;

# 47 per cent lower rate of limb deformities;

# 58 per cent reduction in cases of cleft palate;

# 52 per cent decrease in urinary-tract defects;

# 63 per cent drop in hydrocephalus (a dangerous accumulation of cerebrospinal fluid on the brain).

The research did not show any decrease in the number of cases of Down syndrome, pyloric stenosis (which causes chronic vomiting), undescended testis or hypospadias (a malformation of the penis).

summary of the article by Andre Picard, Globe and Mail

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